hybridization-based in situ sequencing hybiss Search Results


situ sequencing  (Spatial Transcriptomics Inc)
86
Spatial Transcriptomics Inc situ sequencing
A Experimental outline including the location of sample collection from donated healthy human lungs, and the methods used for the mRNA-based cell type mapping. 1—trachea, 2—proximal bronchi, 3a—bottom part of upper left lobe, 3b—top part of upper left lobe, 3c—bottom part of lower left lobe. HybISS Hybridization-based in situ <t>sequencing,</t> SCRINSHOT Single-Cell Resolution IN Situ Hybridization On Tissues, RRST RNA-Rescue Spatial Transcriptomics. B UMAP of cells after leiden clustering profiled with HybISS, colored by the assigned cell type (35 cell types presented). Gen general, adv adventitial, nan not annotated. C Heatmap of relative abundance of clustered cell types between locations demonstrating their frequency across the profiled regions. Similarity in cell type composition between three distal lung regions can be assessed by hierarchical clustering dendrogram on the left side. D Representative histological images from four biological replicates of an analysed trachea (donor 4) and a distal lung (donor 1) biopsies with hematoxyllin and eosin (H&E) staining (up) coupled to the maps of cell types identified by HybISS on top of nuclei (DAPI, white) in the same sections (down). Spots represent detected transcripts, colored according to the corresponding cell type of the cell they were assigned to. Colors as in Fig. 1B. Dashed lines indicate the approximate borders of histologic compartments. SMG submucosal gland, aw airway, alv alveolar region, bv blood vessel. Scale bar 200 µm. E Cell type neighborhood enrichment graph representing cell types as nodes, and edges indicating a positive neighborhood enrichment (>2) between cell types across the profiled sections. Suggested neighborhoods are shown as bubbles. Node colors as in Fig. 1B. Source data are provided as a Source Data file.
Situ Sequencing, supplied by Spatial Transcriptomics Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hybridization-based+in+situ+sequencing+hybiss/pmc12589588-37-3-15?v=Spatial+Transcriptomics+Inc
Average 86 stars, based on 1 article reviews
situ sequencing - by Bioz Stars, 2026-07
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rrst rna rescue spatial transcriptomics  (Spatial Transcriptomics Inc)
86
Spatial Transcriptomics Inc rrst rna rescue spatial transcriptomics
A Experimental outline including the location of sample collection from donated healthy human lungs, and the methods used for the mRNA-based cell type mapping. 1—trachea, 2—proximal bronchi, 3a—bottom part of upper left lobe, 3b—top part of upper left lobe, 3c—bottom part of lower left lobe. HybISS Hybridization-based in situ <t>sequencing,</t> SCRINSHOT Single-Cell Resolution IN Situ Hybridization On Tissues, RRST RNA-Rescue Spatial Transcriptomics. B UMAP of cells after leiden clustering profiled with HybISS, colored by the assigned cell type (35 cell types presented). Gen general, adv adventitial, nan not annotated. C Heatmap of relative abundance of clustered cell types between locations demonstrating their frequency across the profiled regions. Similarity in cell type composition between three distal lung regions can be assessed by hierarchical clustering dendrogram on the left side. D Representative histological images from four biological replicates of an analysed trachea (donor 4) and a distal lung (donor 1) biopsies with hematoxyllin and eosin (H&E) staining (up) coupled to the maps of cell types identified by HybISS on top of nuclei (DAPI, white) in the same sections (down). Spots represent detected transcripts, colored according to the corresponding cell type of the cell they were assigned to. Colors as in Fig. 1B. Dashed lines indicate the approximate borders of histologic compartments. SMG submucosal gland, aw airway, alv alveolar region, bv blood vessel. Scale bar 200 µm. E Cell type neighborhood enrichment graph representing cell types as nodes, and edges indicating a positive neighborhood enrichment (>2) between cell types across the profiled sections. Suggested neighborhoods are shown as bubbles. Node colors as in Fig. 1B. Source data are provided as a Source Data file.
Rrst Rna Rescue Spatial Transcriptomics, supplied by Spatial Transcriptomics Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hybridization-based+in+situ+sequencing+hybiss/pm41193468-63-13-15?v=Spatial+Transcriptomics+Inc
Average 86 stars, based on 1 article reviews
rrst rna rescue spatial transcriptomics - by Bioz Stars, 2026-07
86/100 stars
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nephrology intron seqfish intron  (Wolters Kluwer Health)
86
Wolters Kluwer Health nephrology intron seqfish intron
A Experimental outline including the location of sample collection from donated healthy human lungs, and the methods used for the mRNA-based cell type mapping. 1—trachea, 2—proximal bronchi, 3a—bottom part of upper left lobe, 3b—top part of upper left lobe, 3c—bottom part of lower left lobe. HybISS Hybridization-based in situ <t>sequencing,</t> SCRINSHOT Single-Cell Resolution IN Situ Hybridization On Tissues, RRST RNA-Rescue Spatial Transcriptomics. B UMAP of cells after leiden clustering profiled with HybISS, colored by the assigned cell type (35 cell types presented). Gen general, adv adventitial, nan not annotated. C Heatmap of relative abundance of clustered cell types between locations demonstrating their frequency across the profiled regions. Similarity in cell type composition between three distal lung regions can be assessed by hierarchical clustering dendrogram on the left side. D Representative histological images from four biological replicates of an analysed trachea (donor 4) and a distal lung (donor 1) biopsies with hematoxyllin and eosin (H&E) staining (up) coupled to the maps of cell types identified by HybISS on top of nuclei (DAPI, white) in the same sections (down). Spots represent detected transcripts, colored according to the corresponding cell type of the cell they were assigned to. Colors as in Fig. 1B. Dashed lines indicate the approximate borders of histologic compartments. SMG submucosal gland, aw airway, alv alveolar region, bv blood vessel. Scale bar 200 µm. E Cell type neighborhood enrichment graph representing cell types as nodes, and edges indicating a positive neighborhood enrichment (>2) between cell types across the profiled sections. Suggested neighborhoods are shown as bubbles. Node colors as in Fig. 1B. Source data are provided as a Source Data file.
Nephrology Intron Seqfish Intron, supplied by Wolters Kluwer Health, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hybridization-based+in+situ+sequencing+hybiss/10__1681_slash_asn__0000001023-226-13-2?v=Wolters+Kluwer+Health
Average 86 stars, based on 1 article reviews
nephrology intron seqfish intron - by Bioz Stars, 2026-07
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cosmx fluorescent probe hybridisation  (Bruker Corporation)
97
Bruker Corporation cosmx fluorescent probe hybridisation
A Experimental outline including the location of sample collection from donated healthy human lungs, and the methods used for the mRNA-based cell type mapping. 1—trachea, 2—proximal bronchi, 3a—bottom part of upper left lobe, 3b—top part of upper left lobe, 3c—bottom part of lower left lobe. HybISS Hybridization-based in situ <t>sequencing,</t> SCRINSHOT Single-Cell Resolution IN Situ Hybridization On Tissues, RRST RNA-Rescue Spatial Transcriptomics. B UMAP of cells after leiden clustering profiled with HybISS, colored by the assigned cell type (35 cell types presented). Gen general, adv adventitial, nan not annotated. C Heatmap of relative abundance of clustered cell types between locations demonstrating their frequency across the profiled regions. Similarity in cell type composition between three distal lung regions can be assessed by hierarchical clustering dendrogram on the left side. D Representative histological images from four biological replicates of an analysed trachea (donor 4) and a distal lung (donor 1) biopsies with hematoxyllin and eosin (H&E) staining (up) coupled to the maps of cell types identified by HybISS on top of nuclei (DAPI, white) in the same sections (down). Spots represent detected transcripts, colored according to the corresponding cell type of the cell they were assigned to. Colors as in Fig. 1B. Dashed lines indicate the approximate borders of histologic compartments. SMG submucosal gland, aw airway, alv alveolar region, bv blood vessel. Scale bar 200 µm. E Cell type neighborhood enrichment graph representing cell types as nodes, and edges indicating a positive neighborhood enrichment (>2) between cell types across the profiled sections. Suggested neighborhoods are shown as bubbles. Node colors as in Fig. 1B. Source data are provided as a Source Data file.
Cosmx Fluorescent Probe Hybridisation, supplied by Bruker Corporation, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hybridization-based+in+situ+sequencing+hybiss/pm39787997-83-191-190?v=Bruker+Corporation
Average 97 stars, based on 1 article reviews
cosmx fluorescent probe hybridisation - by Bioz Stars, 2026-07
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capture region mrna whole transcriptome  (Complete Genomics Inc)
99
Complete Genomics Inc capture region mrna whole transcriptome
A Experimental outline including the location of sample collection from donated healthy human lungs, and the methods used for the mRNA-based cell type mapping. 1—trachea, 2—proximal bronchi, 3a—bottom part of upper left lobe, 3b—top part of upper left lobe, 3c—bottom part of lower left lobe. HybISS Hybridization-based in situ <t>sequencing,</t> SCRINSHOT Single-Cell Resolution IN Situ Hybridization On Tissues, RRST RNA-Rescue Spatial Transcriptomics. B UMAP of cells after leiden clustering profiled with HybISS, colored by the assigned cell type (35 cell types presented). Gen general, adv adventitial, nan not annotated. C Heatmap of relative abundance of clustered cell types between locations demonstrating their frequency across the profiled regions. Similarity in cell type composition between three distal lung regions can be assessed by hierarchical clustering dendrogram on the left side. D Representative histological images from four biological replicates of an analysed trachea (donor 4) and a distal lung (donor 1) biopsies with hematoxyllin and eosin (H&E) staining (up) coupled to the maps of cell types identified by HybISS on top of nuclei (DAPI, white) in the same sections (down). Spots represent detected transcripts, colored according to the corresponding cell type of the cell they were assigned to. Colors as in Fig. 1B. Dashed lines indicate the approximate borders of histologic compartments. SMG submucosal gland, aw airway, alv alveolar region, bv blood vessel. Scale bar 200 µm. E Cell type neighborhood enrichment graph representing cell types as nodes, and edges indicating a positive neighborhood enrichment (>2) between cell types across the profiled sections. Suggested neighborhoods are shown as bubbles. Node colors as in Fig. 1B. Source data are provided as a Source Data file.
Capture Region Mrna Whole Transcriptome, supplied by Complete Genomics Inc, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hybridization-based+in+situ+sequencing+hybiss/pm39787997-83-109-115?v=Complete+Genomics+Inc
Average 99 stars, based on 1 article reviews
capture region mrna whole transcriptome - by Bioz Stars, 2026-07
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Image Search Results


A Experimental outline including the location of sample collection from donated healthy human lungs, and the methods used for the mRNA-based cell type mapping. 1—trachea, 2—proximal bronchi, 3a—bottom part of upper left lobe, 3b—top part of upper left lobe, 3c—bottom part of lower left lobe. HybISS Hybridization-based in situ sequencing, SCRINSHOT Single-Cell Resolution IN Situ Hybridization On Tissues, RRST RNA-Rescue Spatial Transcriptomics. B UMAP of cells after leiden clustering profiled with HybISS, colored by the assigned cell type (35 cell types presented). Gen general, adv adventitial, nan not annotated. C Heatmap of relative abundance of clustered cell types between locations demonstrating their frequency across the profiled regions. Similarity in cell type composition between three distal lung regions can be assessed by hierarchical clustering dendrogram on the left side. D Representative histological images from four biological replicates of an analysed trachea (donor 4) and a distal lung (donor 1) biopsies with hematoxyllin and eosin (H&E) staining (up) coupled to the maps of cell types identified by HybISS on top of nuclei (DAPI, white) in the same sections (down). Spots represent detected transcripts, colored according to the corresponding cell type of the cell they were assigned to. Colors as in Fig. 1B. Dashed lines indicate the approximate borders of histologic compartments. SMG submucosal gland, aw airway, alv alveolar region, bv blood vessel. Scale bar 200 µm. E Cell type neighborhood enrichment graph representing cell types as nodes, and edges indicating a positive neighborhood enrichment (>2) between cell types across the profiled sections. Suggested neighborhoods are shown as bubbles. Node colors as in Fig. 1B. Source data are provided as a Source Data file.

Journal: Nature Communications

Article Title: Spatial single-cell atlas reveals regional variations in healthy and diseased human lung

doi: 10.1038/s41467-025-65704-0

Figure Lengend Snippet: A Experimental outline including the location of sample collection from donated healthy human lungs, and the methods used for the mRNA-based cell type mapping. 1—trachea, 2—proximal bronchi, 3a—bottom part of upper left lobe, 3b—top part of upper left lobe, 3c—bottom part of lower left lobe. HybISS Hybridization-based in situ sequencing, SCRINSHOT Single-Cell Resolution IN Situ Hybridization On Tissues, RRST RNA-Rescue Spatial Transcriptomics. B UMAP of cells after leiden clustering profiled with HybISS, colored by the assigned cell type (35 cell types presented). Gen general, adv adventitial, nan not annotated. C Heatmap of relative abundance of clustered cell types between locations demonstrating their frequency across the profiled regions. Similarity in cell type composition between three distal lung regions can be assessed by hierarchical clustering dendrogram on the left side. D Representative histological images from four biological replicates of an analysed trachea (donor 4) and a distal lung (donor 1) biopsies with hematoxyllin and eosin (H&E) staining (up) coupled to the maps of cell types identified by HybISS on top of nuclei (DAPI, white) in the same sections (down). Spots represent detected transcripts, colored according to the corresponding cell type of the cell they were assigned to. Colors as in Fig. 1B. Dashed lines indicate the approximate borders of histologic compartments. SMG submucosal gland, aw airway, alv alveolar region, bv blood vessel. Scale bar 200 µm. E Cell type neighborhood enrichment graph representing cell types as nodes, and edges indicating a positive neighborhood enrichment (>2) between cell types across the profiled sections. Suggested neighborhoods are shown as bubbles. Node colors as in Fig. 1B. Source data are provided as a Source Data file.

Article Snippet: HybISS Hybridization-based in situ sequencing, SCRINSHOT Single-Cell Resolution IN Situ Hybridization On Tissues, RRST RNA-Rescue Spatial Transcriptomics.

Techniques: Hybridization, In Situ, Sequencing, In Situ Hybridization, Staining